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Cardiorespiratory abnormalities in early and advances stage mouse models of Duchenne muscular dystrophy
(University of Missouri--Columbia, 2021)
was determined in histological sections using planimetry. We found that 16-month-old DMD hearts were in early stages of myocardial fibrosis, with 9.6 +/- 0.04 percent in the RV (n=3) and 2.1 +/- 0.01 percent in the LV (n=3). In contrast, the dystrophic changes...